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Should Patients With Diabetes Drink to Their Health?
Michael H. Criqui, MD, MPH;
Beatrice A. Golomb, MD, PhD
JAMA. 1999;282:279-280.
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In this issue of THE JOURNAL, Valmadrid and other investigators from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR)1 report a progressive reduction in risk of coronary heart disease (CHD) death and overall mortality with increasing levels of alcohol consumption, within the mild to moderate range, in patients with older-onset diabetes. This finding complements and extends findings from numerous previous studies that have reported reduced CHD and all-cause mortality in light to moderate drinkers.2 Case-control, population, and twin studies have observed a relation of moderate alcohol consumption and reduced insulin resistance (with lower fasting and postprandial glucose and insulin levels).3-5 Other studies, meanwhile, have found that higher amounts of acute or long-term alcohol ingestion increase insulin resistance,6-7 as well as triglyceride levels, blood pressure, and all-cause mortality. The present study by Valmadrid et al was unable to evaluate risk with . . . [Full Text of this Article]
Author Affiliations: Departments of Family and Preventive Medicine (Dr Criqui) and Medicine (Drs Criqui and Golomb), University of California, San Diego, La Jolla, Calif.
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JAMA. 1999;282(3):239-246.
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