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Noncompliance May Cause Half of Antihypertensive Drug "Failures"
Joan Stephenson, PhD
JAMA. 1999;282:313-314.
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As many as half of "failures" of treatment to bring elevated blood pressure down to normal levels may be due to unrecognized lapses by patients in taking antihypertensive drugs as prescribed, according to a new study by a team of researchers from the University of Lausanne, Switzerland.
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Patients' pill-taking behavior can be monitored with the help of a pill container outfitted with a microchip that records each time the container is opened and closed. The physician can download this information into a computer, which generates a chart that shows when and how often doses were skipped. (Illustration Credit: AARDEX Ltd)
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In general, says the Sixth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure, pharmacological therapy for uncontrolled blood pressure should proceed in stepwise fashion. The physician usually prescribes a low dosage of a diuretic or -blocker, moves to higher . . . [Full Text of this Article]
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