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To the Editor: In their exploratory and confirmatory factor analyses of symptoms of US Air Force Gulf War veterans, Dr Fukuda and colleagues¹ from the Centers for Disease Control and Prevention (CDC) replicated 2 of the 3 syndromes that we identified by factor analysis in Gulf War veterans of a US Naval reserve unit.² Their syndrome factors 1 and 2 are virtually identical to our factors 1 and 3 (Table 1).

Table appears in full text version. Table. Agreement Between Factor Analysis–Derived Case Definitions of Gulf War Syndrome*

However, 2 methodological problems prevented Fukuda et al from identifying our syndrome factor 2 ("confusion-ataxia"). First, the investigators did not measure the symptoms that would have identified it (Table 1). Second, they inadvertently excluded those with our syndrome 2 from their sample. By studying only veterans remaining in the service 4 years after the war, they excluded the 70% of original members of those . . . [Full Text of this Article]

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