 |
|
Susceptibility to Gonococcal Infection During the Menstrual Cycle
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
To the Editor: Neisseria gonorrhoeae is a common etiologic agent of pelvic inflammatory disease (PID).1 The development of PID is likely determined by both host susceptibility and the virulence of the organism, and there is clinical evidence that changes in host susceptibility are influenced by hormonal status. For instance, the incidence of gonococcal PID symptoms is highest during the early proliferative phase of the menstrual cycle, and PID is less prevalent among women who use oral contraceptives.1-4 Furthermore, men rarely develop ascending gonococcal infections. Since complement activity is an important defense against PID,5 we wanted to determine if complement activity is cyclic and thus correlated with resistance to gonococcal infection.
Method
To investigate possible cyclic changes in serum properties, we evaluated the antibacterial activity of multiple serum samples obtained from 4 female volunteers, aged 25 to 35 years, at different phases of the menstrual cycle. All women had regular 28-day cycles, . . . [Full Text of this Article]
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Specific Antibody Levels at the Cervix During the Menstrual Cycle of Women Vaccinated With Human Papillomavirus 16 Virus-Like Particles
Nardelli-Haefliger et al.
JNCI J Natl Cancer Inst 2003;95:1128-1137.
ABSTRACT
| FULL TEXT
Complement Factor I Deficiency Associated With Recurrent Meningitis Coinciding With Menstruation
Gonzalez-Rubio et al.
Arch Neurol 2001;58:1923-1928.
ABSTRACT
| FULL TEXT
|
