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C. Noel Bairey Merz, MD; Maura Paul-Labrador, MPH; Piyanuj Vongvanich, MD

JAMA. 2000;283:1476-1478.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Exercise training is an effective treatment for coronary artery disease. Medically supervised exercise has been demonstrated to halt progression and enhance regression of angiographic stenoses,¹ reduce myocardial stress perfusion defects,² enhance quality of life,³ and reduce mortality.^4-5 Compared with other currently available therapies for coronary artery disease, the 25% risk reduction observed with exercise is comparable with the 20% achieved with aspirin,⁶ the 20% with blockers,⁷ and the 15% observed with angiotensin-converting enzyme inhibitors.⁸ Because the studies demonstrating overall mortality reduction were performed prior to the use of thrombolysis and aggressive revascularization therapy, the net additional benefit of supervised exercise in these lower-risk populations is unknown. Nevertheless, based on these and other randomized controlled trial data, the Agency for Health Care Policy and Research Cardiac Rehabilitation Guidelines⁹ call for universal application of medically supervised exercise for the more than . . . [Full Text of this Article]

Author Affiliations: Preventive and Rehabilitative Cardiac Center, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Center; and the Department of Medicine, University of California School of Medicine, Los Angeles, Calif.

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