This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Michael Fitzpatrick

JAMA. 2000;283:1948-1949.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Tokyo—Working with investigators in the thoracic surgery department at Keio University School of Medicine, investigators here at the Central Research Laboratory of Hitachi Ltd and at the Hitachi Chemical Research Center in Irvine, Calif, have developed a method to detect the early spread of lung cancer using genetic analysis of cancer cells carried in the bloodstream.

The collaborating teams said they analyzed 121 specific genes (of 10,000 known to be expressed in lung cancer) in biopsied tissue from patients with the disease. In experiments using just six of the 121 genes, they have detected early metastasis in tissue from patients having various stages of the disease, said Masato Mitsuhashi, MD, PhD, who heads the team working in Irvine.

"Since the symptoms of lung cancer often do not appear until the tumors spread to nearby lymph nodes or elsewhere, it is difficult to make the early diagnosis only . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?