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Delay in Treating Schizophrenia May Narrow Therapeutic Window of Opportunity
Joan Stephenson, PhD
JAMA. 2000;283:2091-2092.
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New YorkRecognizing and treating the first episode of psychosis in people with schizophrenia should be a priority for the mental health community because delay reduces the likelihood of a good therapeutic response, said experts gathered here for the 2nd International Conference on Early Psychosis. Recent studies have demonstrated that in addition to alleviating the suffering of people in the early stages of schizophrenia, prompt treatment after the onset of symptoms is linked to a better prognosis.
TANTALIZING CLUES
Scientists are uncertain why treatment delays after the emergence of psychotic symptoms decrease the rate and degree of remission of symptoms in patients with schizophrenia. But along with emerging evidence that schizophrenia is, in part, a neurodevelopmental disorder, there are now some tantalizing clues that disease progression may depend on neurodegenerative processes that occur afteror even beforethe emergence of psychotic symptoms, said Jeffrey Lieberman, MD, of the University . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Psychosocial Treatment for First-Episode Psychosis: A Research Update
Penn et al.
Am. J. Psychiatry 2005;162:2220-2220.
ABSTRACT
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