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  Vol. 283 No. 19, May 17, 2000 TABLE OF CONTENTS
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Easy on the Antioxidants

Joan Stephenson, PhD

JAMA. 2000;283:2514.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Interest in antioxidants such as vitamins C and E, selenium, and carotenoids has soared in recent years, in large part due to epidemiological studies suggesting that foods rich in these substances reduce the risk of chronic diseases. But a new report from the Institute of Medicine warns that people who ingest these substances in the form of dietary supplements should be aware that benefits are unproven and large doses can harm rather than help.


Recommended intakes of some antioxidants have been increased, and first-ever upper limits have been established.

Based on the available scientific data on both beneficial and harmful health effects of certain antioxidants, a panel of experts said that the recommended daily intake of vitamins C and E should be increased slightly above previous levels. The panel, for the first time ever, also established upper limits to prevent adverse health effects from megadoses, such as . . . [Full Text of this Article]







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