 |
|
Recent Advances in Wound Healing
Ysabel M. Bello, MD;
Tania J. Phillips, MD
JAMA. 2000;283:716-718.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
INTRODUCTION
Over the past decade, a variety of new therapies have become available for patients with acute and chronic wounds. Enthusiasm for these treatments should be tempered by the understanding that treatment of the wound's underlying origin is paramount and that cost and cost-effectiveness should be considered closely.
Physiology
Wound healing includes 3 overlapping phases: inflammation, tissue formation, and tissue remodeling. This involves a complex, dynamic series of events including clotting, inflammation, granulation tissue formation, epithelialization, neovascularization, collagen synthesis, and wound contraction.1 These events overlap in time, and involve a complex array of cytokines secreted by platelets, macrophages, neutrophils, fibroblasts, and epidermal cells.1
Estrogen may play a role in wound healing.2-3 In one study, aging in healthy females was associated with a reduced rate of wound healing and reduced levels of transforming growth factor  1, but an improved quality of scarring.2 Estrogen replacement therapy . . . [Full Text of this Article]
Wound Types
Venous Ulcers
Arterial Ulcers
Neuropathic Ulcers
Pressure Ulcers
Wound Dressings
Other Wound Treatments
Skin Substitutes Epidermal Grafts Dermal Replacements Composite Grafts Growth Factors Physical Modalities Drugs
Author Affiliations: Boston University School of Medicine, Boston, Mass.
RELATED LETTER
Adjunctive Therapies for Wound Healing
Thomas M. Bozzuto, Caroline E. Fife, William P. Graham III, Ysabel M. Bello, and Tania J. Phillips
JAMA. 2000;284(1):40-41.
EXTRACT
| FULL TEXT
RELATED ARTICLE
February 9, 2000
JAMA. 2000;283(6):817-818.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Transdermal Sustained-Delivery Oxygen Improves Epithelial Healing in a Rabbit Ear Wound Model
Said et al.
Arch Surg 2005;140:998-1004.
ABSTRACT
| FULL TEXT
Pressure Ulcer Prevention and Management
Lyder
JAMA 2003;289:223-226.
FULL TEXT
Skin Grafting of Venous Ulcers: A Review of its Current Role
Becker et al.
INT J LOW EXTREM WOUNDS 2002;1:236-241.
ABSTRACT
Immobilized Thrombin Receptor Agonist Peptide Accelerates Wound Healing in Mice
Strukova et al.
CLIN APPL THROMB HEMOST 2001;7:325-329.
ABSTRACT
Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice
GALLUCCI et al.
FASEB J. 2000;14:2525-2531.
ABSTRACT
| FULL TEXT
Adjunctive Therapies for Wound Healing
Bozzuto et al.
JAMA 2000;284:40-41.
FULL TEXT
|
