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Richard P. Wenzel, MD, MSc

JAMA. 2000;283:1057-1059.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 1743 headline in The London Magazine cited "news from Rome of a contagious distemper called the influenza."¹ At that time, the pathogenic "influence" visited on the citizens of Italy may have been thought to be occult or astral in origin. It is now well known, however, that a family of RNA orthomyxoviruses causes the deadly respiratory infections, which spread from person to person by the airborne route. In 1918-1919, an influenza pandemic killed 21 million people worldwide and more than 500,000 in the United States.² Currently, the Centers for Disease Control and Prevention (CDC) estimates that 20,000 people die in the United States each year from influenza, and 110,000 are hospitalized.³

The Advisory Committee on Immunization Practices of the CDC³ recommends annual vaccination for all people older than 65 years, persons residing in nursing homes or long-term care facilities, and for those with chronic . . . [Full Text of this Article]

Author Affiliation: Department of Internal Medicine, Virginia Commonwealth University, Richmond.

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