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Charles Marwick

JAMA. 2000;284:1231-1232.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Bethesda, Md—In December 1993, concerned about the increasing numbers of animals being diagnosed as having bovine spongiform encephalopathy (BSE or "mad cow disease") in countries abroad, the US Food and Drug Administration (FDA) recommended that US manufacturers of medicinal and biological products not use materials from animals in countries reporting BSE. These materials include serum, bone, and nervous system tissue. The agency's position was that the agent of BSE could be present in these materials and transmitted to patients, where it might cause Creutzfeld-Jakob disease (CJD).

At the time, the countries known to have cattle infected with BSE were Great Britain (which reported the most cases, more than 17,000 in 1993), France, the Irish Republic, Northern Ireland, Switzerland, and Oman. Other countries reported cases of BSE that were discovered in imported cattle. A list of all these countries is maintained by the US Department of Agriculture.

Concern . . . [Full Text of this Article]

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