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Perinatal Brain Injury in Preterm Infants and Later Neurobehavioral Function
Maureen Hack, MB, ChB;
H. Gerry Taylor, PhD
JAMA. 2000;284:1973-1974.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The increase in survival of preterm infants that has resulted mainly from pharmacological and technological advances in perinatal care in the last decade has been associated with a growing concern about the neurodevelopmental outcomes of the infants, especially those of extremely low birth weight and gestational age.1-2 Poor outcomes during early childhood include global cognitive delay, cerebral palsy, blindness, and deafness. By school age, poor academic achievement, behavioral difficulties, and poor social and adaptive functioning become evident in children without obvious neurodevelopmental impairments. These children have lower intelligence scores when compared with those of normal birth weight, and on neuropsychological testing, they perform more poorly on measures of attention, executive function, memory, spatial skills, and fine and gross motor function. Problems with these skills are evident even in children with normal intelligence and no overt neurosensory abnormalities, although detailed neurologic examinations have . . . [Full Text of this Article]
Author Affiliation: Department of Pediatrics, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio.
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