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Maybe Someday, but Not Yet

Paul S. Frame, MD

JAMA. 2000;284:1980-1983.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Lung cancer is the leading cause of cancer death worldwide and accounts for 28% of all cancer deaths in the United States.¹ It is largely a preventable disease. In the United States, more than 90% of lung cancer cases are related to cigarette smoking. Treatment of lung cancer is not very effective and has changed little in the past 40 years. Surgical resection of localized tumors is the only potentially curative treatment, and many tumors are not resectable at the time of diagnosis. Overall current 5-year survival rates are 8% to 14% for whites and 5% to 11% for blacks.²

In view of the large burden of suffering and the poor prognosis for persons with the disease, it is not surprising that screening for the early detection of lung cancer at a curable stage has been a research priority for many years. Indeed, 8 prospective studies . . . [Full Text of this Article]

Historical Perspective

Author Affiliations: Tri-County Family Medicine, Cohocton, NY, and University of Rochester School of Medicine and Dentistry, Rochester, NY.

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