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Joan Stephenson, PhD

JAMA. 2000;284:296.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Two rival teams of scientists announced last month they had assembled a rough draft of the "book of life"—the human genetic code. For this vital instruction manual, researchers have been working to catalog the identity and location of each of the estimated 3 billion chemical base pairs in human DNA.

The groups are the publicly financed Human Genome Project, largely funded by the National Institutes of Health and the London-based Wellcome Trust, and Celera Genomics of Rockville, Md. The public consortium said it had produced a rough draft that includes some 97% of the genome, with about 85% completed in fine detail. Celera claimed that it had sequenced 99%.

Much work remains to be done to fill in gaps in the rough draft and improvethe overall sequencing accuracy to 99.99%, the researchers said. But thousands of genes have already been identified from the genome sequence, with many . . . [Full Text of this Article]

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