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JAMA. 2000;284:299-300.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

MMWR. 2000;49;535-538

2 tables omitted

In the United States, pregnancies associated with assisted reproductive technology (ART) or ovulation-inducing drugs are more likely to result in multiple births than spontaneously conceived pregnancies.¹ In addition, triplet and higher-order multiple births are at greater risk than singleton births to be preterm (37 completed weeks' gestation), low birthweight (LBW) (i.e., 2500 g), or very low birthweight (i.e., <1500 g), resulting in higher infant morbidity and mortality.² Because preterm and LBW infants often require costly neonatal care and long-term developmental follow-up, the continuing increase in triplet and higher-order multiple births causes concern among health-care providers and policymakers.³ This report provides estimates of the contribution of ART and ovulation-inducing drugs to these birth outcomes for 1996 and 1997, and summarizes trends during 1980-1997, which indicate that the ratio of triplet and higher-order multiple births has more than quadrupled and that a large proportion of this . . . [Full Text of this Article]

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