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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: We were surprised by the results presented by Dr Schutzer and colleagues¹ reporting on an immune complex diagnostic method for Lyme disease; this method was first described by Schutzer et al almost 10 years ago.² Our experience with the immune complex approach differs substantially from theirs.

In February 1999, Dr Schutzer and Dr Coyle participated in a blinded study (referred to as a pilot study in their article) with the Centers for Disease Control and Prevention (CDC), in which the immune complex approach was compared with the nationally recommended 2-tier serologic testing.³ The CDC provided 60 blinded and coded samples to each participating group: 25 samples from 13 patients with early, culture-confirmed Lyme disease, 25 samples from control subjects with no history of Lyme disease, and 5 repeated samples from each of these 2 sample groups.

The comparative findings of this evaluation (Table 1) were . . . [Full Text of this Article]

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Borrelia burgdorferi–Specific Immune Complexes in Acute Lyme Disease
Steven E. Schutzer, P. K. Coyle, Patrick Reid, and Bart Holland
JAMA. 1999;282(20):1942-1946.
ABSTRACT | FULL TEXT