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Industry-Sponsored Grand Rounds and Prescribing Behavior
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To the Editor: We recently discovered a sudden and sustained 3-fold increase in the pharmacy expenditures for quetiapine fumarate, an atypical antipsychotic agent, at the Minneapolis Veterans Affairs Medical Center (VAMC). This occurred in April 2000, which was 28 months after the drug became available in the United States and 5 months after it was placed on the hospital formulary. We investigated this sudden and dramatic increase in prescription costs for this drug at our institution.
Methods
Because the VAMC has a closed panel of prescribers, we were able to obtain data about prescribing behavior at the individual level, as well as the cost and dosage per prescription. Pharmaceutical representatives must sign in prior to visiting the medical staff, and thus we were able to examine the frequency of visits from representatives of the manufacturer. We also looked at the content and sponsorship of all presentations made to the medical staff . . . [Full Text of this Article]
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JAMA. 2001;286(8):917-918.
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