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Tuberculosis Treatment Interruptions—Ivanovo Oblast, Russian Federation, 1999
JAMA. 2001;285:1953-1954.
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MMWR. 2001;50:201-204
In the Russian Federation, the number of tuberculosis (TB) cases increased from 45,000 (34 per 100,000 population) in 1991 to 124,000 (85 per 100,000 population) in 1999.1 In 1995, the World Health Organization (WHO) implemented a pilot TB control project in the Ivanovo oblast of the Russian Federation (1995 population: 1.3 million), located 175 miles northeast of Moscow. The project is based on the following five elements of the WHO directly observed treatment, short-course (DOTS) strategy for controlling TB: government commitment, laboratory-based diagnosis, a reliable supply of anti-TB medications, direct supervision of standardized treatment, and a recording and reporting system that permits evaluation of treatment outcomes. In most settings, implementing this strategy has resulted in cure rates of  85%2-3; however, little improvement occurred in cure rates in Ivanovo after implementation of this strategy in 1995.4-5 Although 17% of these poor outcomes were attributed to primary multidrug-resistant TB . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Tuberculosis treatment outcomes in Europe: a systematic review
Faustini et al.
Eur Respir J 2005;26:503-510.
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