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  Vol. 285 No. 17, May 2, 2001 TABLE OF CONTENTS
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Basic Science and Translational Research

Call for Papers

Phil B. Fontanarosa, MD; Catherine D. DeAngelis, MD,MPH

JAMA. 2001;285:2246.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

From bench to bedside, from concept to clinical application, and from discovery to dissemination, translating novel scientific insights into new approaches for prevention, diagnosis, and treatment of disease is the ultimate goal of medical research. Today, with the sequencing of the human genome and the unprecedented levels of private and public support for basic and clinical research, opportunities for discoveries and progress in biomedical science have never been greater.1

Advances in medical research result from a series of interrelated and interdependent steps involving basic scientists, applied researchers, and clinical investigators. This translational research process includes verification of basic hypotheses and observations with in vitro studies, confirmation in animal experiments and perhaps refinement with biomathematical modeling, and clinical testing in phase 1 and phase 2 investigations, and ultimately phase 3 trials.2-3 Likewise, ideas and observations from the clinic can be brought to the . . . [Full Text of this Article]

Author Affiliations: Dr Fontanarosa is Executive Deputy Editor and Dr DeAngelis is Editor, JAMA.



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Basic Science and Translational Research in JAMA
Fontanarosa and DeAngelis
JAMA 2002;287:1728-1728.
FULL TEXT  





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