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Incidence of Dementia and Alzheimer Disease in Nigeria and the United States
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To the Editor: While the article by Dr Hendrie and colleagues1 may be the first to report on geographical differences in Alzheimer disease (AD) incidence, there have been other studies of geographical differences in AD prevalence. The work by White et al2 was the first to show that when people of one ethnic group moved from their homeland to the United States, in this case Japanese moving to Hawaii, the AD prevalence increased dramatically. This finding provided the impetus for a multicountry ecologic study of dietary links to AD using data from 11 countries.3 The data were carefully evaluated for comparable methodology and only high-quality reports were included. As a measure of quality, for countries with several reported AD prevalence rates, the data spread was less than 1% unless urban and rural areas or different ethnic groups were studied. The values ranged from 1.4% in Nigeria to 6.2% among African . . . [Full Text of this Article]
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