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Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults

JAMA. 2001;285:2486-2497.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

The Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III, or ATP III) constitutes the National Cholesterol Education Program's (NCEP's) updated clinical guidelines for cholesterol testing and management. The full ATP III document is an evidence-based and extensively referenced report that provides the scientific rationale for the recommendations contained in the executive summary. ATP III builds on previous ATP reports and expands the indications for intensive cholesterol-lowering therapy in clinical practice. It should be noted that these guidelines are intended to inform, not replace, the physician's clinical judgment, which must ultimately determine the appropriate treatment for each individual.

BACKGROUND

The third ATP report updates the existing recommendations for clinical management of high blood cholesterol. The NCEP periodically produces ATP clinical updates as warranted by advances in . . . [Full Text of this Article]

LDL CHOLESTEROL: THE PRIMARY TARGET OF THERAPY

RISK ASSESSMENT: FIRST STEP IN RISK MANAGEMENT

Method of Risk Assessment: Counting Major Risk Factors and Estimating 10-Year CHD Risk

Role of Other Risk Factors in Risk Assessment

Metabolic Syndrome

The Link Between Risk Assessment and Cost-effectiveness

PRIMARY PREVENTION WITH LDL-LOWERING THERAPY

SECONDARY PREVENTION WITH LDL-LOWERING THERAPY

LDL-LOWERING THERAPY IN 3 RISK CATEGORIES

CHD and CHD Risk Equivalents

Multiple (2+) Risk Factors and 10-Year Risk of 20%

Multiple (2+) Risk Factors and a 10-Year Risk of 10%-20%

Multiple (2+) Risk Factors and a 10-Year Risk of <10%

0-1 Risk Factor

THERAPEUTIC LIFESTYLE CHANGES IN LDL-LOWERING THERAPY

DRUG THERAPY TO ACHIEVE LDL CHOLESTEROL GOALS

Secondary Prevention: Drug Therapy for CHD and CHD Risk Equivalents

LDL-Lowering Drug Therapy for Primary Prevention

BENEFIT BEYOND LDL LOWERING: THE METABOLIC SYNDROME AS A SECONDARY TARGET OF THERAPY

Management of Underlying Causes of the Metabolic Syndrome

Weight Control

Physical Activity

Specific Treatment of Lipid and Nonlipid Risk Factors

SPECIAL ISSUES

Management of Specific Dyslipidemias

Very High LDL Cholesterol (190 mg/dL)

Elevated Serum Triglycerides

Low HDL Cholesterol

Diabetic Dyslipidemia

Special Considerations for Different Population Groups

Middle-Aged Men (35-65 Years)

Women Aged 45-75 Years

Older Adults (Men 65 Years and Women 75 Years)

Younger Adults (Men 20-35 Years; Women 20-45 Years)

Racial and Ethnic Groups

ADHERENCE TO LDL-LOWERING THERAPY



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