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  Vol. 285 No. 21, June 6, 2001 TABLE OF CONTENTS
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Botulinum Toxin in Biowarfare

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: A historical incident illustrates a number of features of botulinum toxin not discussed in the review of bioweaponry by Dr Arnon and colleagues.1

During World War II, the US Office of Strategic Services (OSS) developed a plan for Chinese prostitutes to assassinate high-ranking Japanese officers with whom they sometimes consorted in occupied Chinese cities. Concealing traditional weapons on the women at the appropriate time would obviously be difficult. Therefore, under the direction of Stanley Lovell, the OSS prepared gelatin capsules "less than the size of the head of a common pin"2 containing a lethal dose of botulinum toxin. Wetted, a capsule could be stuck behind the ear or in scalp hair, later to be detached and slipped into the officer's food or drink. The OSS recognized that the normal background of botulism cases would deflect suspicion from the women.2

The capsules were shipped to Chunking, China. The . . . [Full Text of this Article]


RELATED ARTICLE

Botulinum Toxin as a Biological Weapon: Medical and Public Health Management
Stephen S. Arnon, Robert Schechter, Thomas V. Inglesby, Donald A. Henderson, John G. Bartlett, Michael S. Ascher, Edward Eitzen, Anne D. Fine, Jerome Hauer, Marcelle Layton, Scott Lillibridge, Michael T. Osterholm, Tara O'Toole, Gerald Parker, Trish M. Perl, Philip K. Russell, David L. Swerdlow, Kevin Tonat, and for the Working Group on Civilian Biodefense
JAMA. 2001;285(8):1059-1070.
ABSTRACT | FULL TEXT  


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