 |
|
Understanding the Timing of HIV Transmission From Mother to Infant
Athena P. Kourtis, MD, PhD;
Marc Bulterys, MD, PhD;
Steven R. Nesheim, MD;
Francis K. Lee, PhD
JAMA. 2001;285:709-712.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
INTRODUCTION
Mother-to-infant transmission of human immunodeficiency virus (HIV) occurs, without any intervention, at rates of 14% to 42% in various settings.1-2 Determining the timing of such transmission is of great clinical relevance for implementing cost-effective prophylaxis.3-4 Based on virologic detection of HIV during the infant's first 2 days of life, it is generally accepted that about one third of transmissions in nonbreastfeeding women occur during gestation and the remaining two thirds during delivery.5-9 Further support for the notion that most HIV transmission occurs intrapartum includes the association of transmission with prolonged duration of membrane rupture,10-12 the protective effect of elective cesarean delivery,13-16 and a virologic and immunologic pattern of acute primary HIV infection in a majority of affected infants.17 However, these findings could be explained by transmission either very late in gestation or during . . . [Full Text of this Article]
Perinatal Interventions: Cesarean Delivery
Antiviral Regimens
Interpretation
Concurring Evidence
Conclusions
Author Affiliations: Division of Infectious Diseases, Epidemiology and Immunology, Department of Pediatrics, Emory University School of Medicine (Drs Kourtis, Nesheim, and Lee), and Division of HIV/AIDS Prevention, Surveillance and Epidemiology, Centers for Disease Control and Prevention (Dr Bulterys), Atlanta, Ga.
RELATED ARTICLE
February 14, 2001
JAMA. 2001;285(6):819-820.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Rapid Human Immunodeficiency Virus Testing on Labor and Delivery
Rahangdale and Cohan
Obstet Gynecol 2008;112:159-163.
FULL TEXT
Diagnosis of HIV-1 Infection in Children Younger Than 18 Months in the United States
Read and and the Committee on Pediatric AIDS
Pediatrics 2007;120:e1547-e1562.
ABSTRACT
| FULL TEXT
When pregnant women are not screened for HIV
Shrim et al.
cfp 2007;53:1663-1665.
ABSTRACT
| FULL TEXT
Acceptability of perinatal rapid point-of-care HIV testing in an area of low HIV prevalence in the UK
Stokes et al.
Arch. Dis. Child. 2007;92:505-508.
ABSTRACT
| FULL TEXT
Maternal-Fetal Transfer and Amniotic Fluid Accumulation of Nucleoside Analogue Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus-Infected Pregnant Women
Chappuy et al.
Antimicrob. Agents Chemother. 2004;48:4332-4336.
ABSTRACT
| FULL TEXT
Nevirapine and Zidovudine at Birth to Reduce Perinatal Transmission of HIV in an African Setting: A Randomized Controlled Trial
Taha et al.
JAMA 2004;292:202-209.
ABSTRACT
| FULL TEXT
Rapid HIV-1 Testing During Labor: A Multicenter Study
Bulterys et al.
JAMA 2004;292:219-223.
ABSTRACT
| FULL TEXT
Guidelines for Using Antiretroviral Agents among HIV-Infected Adults and Adolescents: The Panel on Clinical Practices for Treatment of HIV
Dybul et al.
ANN INTERN MED 2002;137:381-433.
ABSTRACT
| FULL TEXT
|
