This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA

JAMA. 2001;286:1166.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The FDA has approved M2A Capsule (Given Imaging Ltd, Yoqneam, Israel) for use with other endoscopic and radiological evaluations of the small bowel. The device is 26 mm long and 11 mm wide, is made of biocompatible plastic, and contains a miniature color video camera with a flash, batteries, transmitter, and antenna. The capsule is ingested and propelled through the gastrointestinal tract by natural peristalsis. It transmits the acquired images into a data recorder until the device is excreted.

The capsule was approved primarily on the basis of a trial involving 20 patients with hemoccult-positive stool, iron-deficiency anemia, and/or subacute hematochezia or melena. All patients had undergone unrevealing colonoscopy, gastroscopy, and small bowel radiography within 1 year of enrolling in the study.

A total of 14 small bowel findings were noted in 13 patients by the capsule, push enteroscopy, or laparoscopic surgery. The capsule detected a pathological abnormality in 12 . . . [Full Text of this Article]