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Frank Davidoff, MD; Catherine D. DeAngelis, MD,MPH; Jeffrey M. Drazen, MD; John Hoey, MD; Liselotte Højgaard, MD,DMSc; Richard Horton, FRCP; Sheldon Kotzin, MLS; M. Gary Nicholls, MD; Magne Nylenna, MD; A. John P. M. Overbeke, MD,PhD; Harold C. Sox, MD; Martin B. Van Der Weyden, MD,FRACP,FRCPA; Michael S. Wilkes, MD,PhD

JAMA. 2001;286:1232-1234.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

As editors of general medical journals, we recognize that the publication of clinical research findings in respected peer-reviewed journals is the ultimate basis for most treatment decisions. Public discourse about this published evidence of efficacy and safety rests on the assumption that clinical trials data have been gathered and are presented in an objective and dispassionate manner. This discourse is vital to the scientific practice of medicine because it shapes treatment decisions made by physicians and drives public and private health care policy. We are concerned that the current intellectual environment in which some clinical research is conceived, study subjects . . . [Full Text of this Article]

Author Affiliations: Dr Davidoff is editor emeritus, Annals of Internal Medicine; Dr DeAngelis is editor, JAMA; Dr Drazen is editor-in-chief, New England Journal of Medicine; Dr Hoey is editor, Canadian Medical Association Journal; Dr Højgaard is editor-in-chief, Tidsskrift for Den norske laegeforening (Journal of the Norwegian Medical Association); Dr Horton is editor, The Lancet; Mr Kotzin is executive editor, MEDLINE/Index Medicus; Dr Nicholls is editor, New Zealand Medical Journal; Dr Nylenna is editor-in-chief, Norwegian Medical Association; Dr Overbeke is executive editor, Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine); Dr Sox is editor, Annals of Internal Medicine; Dr Van Der Weyden is editor, The Medical Journal of Australia; and Dr Wilkes is editor, WJM Western Journal of Medicine.

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