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Mike Mitka

JAMA. 2001;286:2083.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

New Orleans—Researchers at Children's Hospital in Boston have shown that amniotic fluid can be a source of cells for fetal tissue engineering and may be a better source than cells harvested from the fetus itself.

In presenting their findings at the American College of Surgeons' Clinical Congress in October, the researchers showed that a 2-mL sample of amniotic fluid obtained by amniocentesis could yield enough cells to create an engineered construct—material containing cells from the fetus, to function as a graft—ready for implantation immediately after birth.

This engineered construct is important because surgeons may need the tissue for use as a patch to repair congenital defects that can't be closed by surgery. But surgeons have been reluctant to use tissue engineering using tissue harvested from the fetus for large defects because this requires a biopsy of the fetal diaphragm or abdominal wall, an invasive procedure. They also . . . [Full Text of this Article]

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