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Osteoporosis, an Underdiagnosed Disease
Charles H. Chesnut III, MD
JAMA. 2001;286:2865-2866.
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The results from the National Osteoporosis Risk Assessment (NORA), the largest study of osteoporosis conducted to date in the United States, have been eagerly awaited by osteoporosis researchers and clinicians. NORA, which commenced in 1997, is a longitudinal observational study involving more than 200 000 postmenopausal women. The study was initially designed to assess the association between osteoporosis risk factors and low bone mineral density (BMD) and to examine the relationship between BMD and other risk factors and short-term (1-year) fracture incidence.1
In this issue of THE JOURNAL, Siris et al2 report the study's initial findings of an unexpectedly high prevalence of unsuspected osteopenia and osteoporosis (as determined by BMD) among generally healthy postmenopausal women followed up in primary care practices. The study also confirms the utility of measurement of BMD at peripheral bone sites using several devices to predict short-term fracture risk. The importance of . . . [Full Text of this Article]
Author Affiliation: Osteoporosis Research Center, University of Washington Medical Center, Seattle.
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