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Commentary by Roger N. Rosenberg, MD

JAMA. 2001;286(22):2869-2870.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

ARCHIVES OF NEUROLOGY

Sequence Analysis of the Human Genome: Implications for the Understanding of Nervous System Function and Disease

Anibal Cravchik, G. Subramanian, Samuel Broder, J. Craig Venter

The recent publication of the sequence of the human genome will accelerate the discovery of new genetic susceptibility factors for human disease, leading to the development of novel diagnostics and therapeutics. The exhaustive analysis of the human genome sequence will be the focus of the biomedical research community for many years to come. In particular, comparative analysis of the available eukaryotic genome sequences is an important approach to further our understanding of gene structure, function, and evolution. Our initial analysis of the human genome sequence has revealed many interesting features that are relevant to nervous system function, evolution, and disease. We analyzed the prominent features of predicted human proteins involved in neuronal function and prepared a . . . [Full Text of this Article]