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Measuring the Quality of Trials of Treatments for Chronic Fatigue Syndrome
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To the Editor: In their systematic review of interventions for chronic fatigue syndrome, Ms Whiting and colleagues1 gave my research2 a low validity score. It was rated as "poor" in 5 categories: baseline comparability of groups, follow-up, dropouts, appropriateness of controls, and control for confounding. However, several trials assessing cognitive behavioral therapy (CBT), which used the same test to control for confounding, had higher dropout rates, and marked differences in baseline scores, were rated as "good." Whiting et al also failed to acknowledge measures in my study that assessed fatigue, disability, and activity. These should have been listed under physical outcomes but Table 2 only refers to the psychological variables and quality of life/health status.
The harshness of the authors' evaluation of my study contrasts sharply with their evaluation of the study by Sharpe et al,3 which was published the same year I completed my dissertation. For example, Whiting et . . . [Full Text of this Article]
RELATED ARTICLE
Interventions for the Treatment and Management of Chronic Fatigue Syndrome: A Systematic Review
Penny Whiting, Anne-Marie Bagnall, Amanda J. Sowden, John E. Cornell, Cynthia D. Mulrow, and Gilbert Ramírez
JAMA. 2001;286(11):1360-1368.
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