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Kernicterus in Full-Term InfantsUnited States, 1994-1998
JAMA. 2001;286:299-300.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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MMWR. 2001;50:491-494
Kernicterus is a preventable life-long neurologic syndrome caused by severe and untreated hyperbilirubinemia during the neonatal period. High levels of bilirubin are toxic to the developing newborn. In full-term infants, hyperbilirubinemia symptoms include severe jaundice, lethargy, and poor feeding. Features of kernicterus may include choreoathetoid cerebral palsy, mental retardation, sensorineural hearing loss, and gaze paresis. Kernicterus is not a reportable condition in the United States, and its prevalence is unknown; however, a pilot registry at a Pennsylvania hospital documented 90 cases in 21 states from 1984 to June 2001 (L. Johnson, Pennsylvania Hospital, Philadelphia, personal communication, 2001). This report summarizes case histories of four full-term, healthy infants who developed kernicterus and underscores that to prevent kernicterus, newborns must be screened and promptly treated for hyperbilirubinemia.1
In early 2001, a national support group for parents of children with kernicterus conducted a survey on kernicterus. A convenience sample of 15 . . . [Full Text of this Article] Case 1 Case 2 Case 3 Case 4
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