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Asthma: Prevalence, Pathogenesis, and Prospects for Novel Therapies
Prescott G. Woodruff, MD,MPH;
John V. Fahy, MD
JAMA. 2001;286:395-398.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The Increasing Prevalence of Asthma
The prevalence of asthma has increased sharply in the United States and around the world in the past 30 years. In the United States, data from the National Health Interview Survey show that the annual prevalence of asthma increased from 3.1% in 1980 to 5.4% in 1994.1 A review of studies performed in 17 countries during the 1960s and repeated in the 1990s confirms an international increase in asthma prevalence.2 Although the increasing prevalence of asthma is a global phenomenon, the scope of the problem differs greatly among countries. The International Study of Asthma and Allergies in Childhood, which examined the prevalence of asthma in 56 different countries in the 1990s, found that prevalence ranged from 2% to 3% in Eastern Europe, Indonesia, Greece, Uzbekistan, India, and Ethiopia to 20% in the United Kingdom, Australia, and New Zealand.3 The finding that affluent . . . [Full Text of this Article]
Current Concepts of Asthma Pathogenesis
Causes of Increased Asthma Prevalence
Novel Therapeutic Strategies
Conclusion
Author Affiliations: The Cardiovascular Research Institute and the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco.
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