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Reducing Risk in College Students

Jay Wenger, MD

JAMA. 2001;286:720-721.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Neisseria meningitidis can cause rapid onset of meningitis and sepsis, leading to death or permanent disability. Meningococcal disease occurs globally, and while the largest outbreaks and preponderance of mortality and morbidity occur in the developing world, the disease continues to strike the young in developed countries.

The N meningitidis organism is usually classified in terms of serogroup, referring to the antigenic properties of the capsular polysaccharide. Most disease in the developed world is caused by organisms of serogroups B, C, Y, and W135 while serogroup A organisms cause the bulk of disease in the developing world.¹ Vaccines prepared with polysaccharides from A, C, Y, and W135 organisms are safe, immunogenic, and have been shown to be effective, particularly in providing short-term and medium-term protection against outbreaks caused by serogroups A and C organisms.² Serogroup B polysaccharide is not immunogenic. Preparation of vaccines from serogroup B proteins has . . . [Full Text of this Article]

Author Affiliation: Expanded Programme on Immunization, World Health Organization, Geneva, Switzerland.

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