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To the Editor: Circadian patterns have been shown in several acute hemorrhagic events, and such patterns could be related to blood pressure rhythms.¹

Methods

We reviewed the records of all patients admitted for intracerebral hemorrage (IH) to the Hospital of Ferrara, Italy, from 1994 through 1997. The diagnosis of IH in 258 patients (136 men, 122 women) was based on either computed tomography, magnetic resonance imaging, or autopsy. Stroke onset time was defined as the earliest time at which definite symptoms or signs were noted, as systematically obtained from patients or bystanders. Precise determination of the onset time was possible in 215 cases (113 men, 102 women; mean age, 73 y). For an additional 26 patients, onset time could not be determined exactly but it could be assigned to 1 of 4 periods: 12:01 AM to 6:00 AM, 6:01 AM to 12:00 PM, 12:01 PM to 6:00 PM, and 6:01 PM . . . [Full Text of this Article]

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