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To the Editor: Dr Moss and colleagues¹ found that among 250 women with lymphangioleiomyomatosis (LAM) who received screening magnetic resonance imaging (MRI), 8 were found to have meningiomas. Although Moss et al divided these 8 patients into 3 groups—normal neurologic findings (6 patients), "sensorimotor abnormalities" (1 patient), and "focal neurologic abnormality (1 patient)"—these clinical terms were not clearly described. It is uncertain whether these symptoms were related to the meningiomas or perhaps to some other cause. No imaging characteristics of the lesions were described, except that 2 patients had multiple meningiomas.

The authors contrast their observed rate of meningioma of 3.2% with a frequency of 0.005% in the general population. However, this latter figure apparently refers to the prevalence of symptomatic meningiomas. Asymptomatic meningiomas are incidental findings in as many as 1.4% of autopsies.² Since none of the women were clearly symptomatic from their lesions, their frequency of meningiomas in . . . [Full Text of this Article]

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