This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in JAMA  Topic Collections  • Revascularization  • Neurology  • Cognitive Disorders  • Cardiovascular System  • Surgery  • Surgical Interventions  • Cardiovascular/ Cardiothoracic Surgery  • Cardiovascular Intervention  • Alert me on articles by topic  Social Bookmarking   What's this?

Daniel B. Mark, MD,MPH; Mark F. Newman, MD

JAMA. 2002;287:1448-1450.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

For much of the 35-year history of coronary artery bypass graft (CABG) surgery, the prevailing belief among cardiovascular physicians was that neurological complications of the procedure were infrequent, consisting primarily of a 1% to 5% incidence of stroke.¹ Some patients reported to their physicians that they were "not quite right" intellectually after the procedure, but such problems were not systematically examined and seemed to be uncommon. Using preoperative and postoperative neuropsychological testing, researchers from many centers have now convincingly demonstrated that measurable cognitive dysfunction is actually a common complication of CABG surgery, with an incidence of up to 80% to 90% at hospital discharge.² This apparent epidemic of operative brain injury has created a major dilemma for the physicians who refer more than 800 000 patients for CABG surgery worldwide each year.³ Because the cognitive dysfunction is often not evident on routine clinical . . . [Full Text of this Article]

Author Affiliations: The Outcomes Research and Assessment Group, Duke Clinical Research Institute (Dr Mark), the Neurologic Outcomes Research Group (Drs Mark and Newman), and the Department of Anesthesiology, Duke University Medical Center (Dr Newman), Durham, NC.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Cognitive Outcome After Off-Pump and On-Pump Coronary Artery Bypass Graft Surgery: A Randomized Trial
Diederik Van Dijk, Erik W. L. Jansen, Ron Hijman, Arno P. Nierich, Jan C. Diephuis, Karel G. M. Moons, Jaap R. Lahpor, Cornelius Borst, Annemieke M. A. Keizer, Hendrik M. Nathoe, Diederick E. Grobbee, Peter P. T. De Jaegere, Cor J. Kalkman, and for the Octopus Study Group
JAMA. 2002;287(11):1405-1412.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Intranasal Deferoxamine Provides Increased Brain Exposure and Significant Protection in Rat Ischemic Stroke
Hanson et al.
J. Pharmacol. Exp. Ther. 2009;330:679-686.
ABSTRACT | FULL TEXT  

Funnel-tipped aortic cannula for reduction of atheroemboli.
White et al.
Ann. Thorac. Surg. 2009;88:551-557.
ABSTRACT | FULL TEXT  

Aortic arch atheroma: stroke reduction in cardiac surgical patients.
Djaiani
SEMIN CARDIOTHORAC VASC ANESTH 2006;10:143-157.
ABSTRACT  

Correlates of Neurocognitive Function of Patients After Off-Pump Coronary Artery Bypass Surgery
Sendelbach et al.
Am J Crit Care 2006;15:290-298.
ABSTRACT | FULL TEXT  

Benefit to quality of life after Off-Pump versus On-Pump coronary bypass surgery
Immer et al.
Ann. Thorac. Surg. 2003;76:27-31.
ABSTRACT | FULL TEXT  

OPCAB surgery: a voyage of discovery back to the future
Ascione and Angelini
Eur Heart J 2003;24:121-124.
FULL TEXT  

OFF-PUMP CORONARY ARTERY BYPASS SURGERY
de Jaegere and Suyker
Heart 2002;88:313-318.
FULL TEXT  

Does Off-Pump CABG Reduce the Risk for Postoperative Cognitive Deficit?
JWatch Emergency Med. 2002;2002:6-6.
FULL TEXT  

On- vs. Off-Pump CABG: Cognitive Outcomes
JWatch Psychiatry 2002;2002:15-15.
FULL TEXT  

On- vs. Off-Pump CABG: Cognitive Outcomes
Journal Watch Cardiology 2002;2002:2-2.
FULL TEXT