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  Vol. 287 No. 15, April 17, 2002 TABLE OF CONTENTS
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Primary Percutaneous Coronary Intervention for All?

Christopher P. Cannon, MD

JAMA. 2002;287:1987-1989.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Reperfusion therapy with thrombolysis or primary percutaneous coronary intervention (PCI) has been a major advance in the treatment of acute ST-segment elevation myocardial infarction (MI), with a 25% reduction in mortality with thrombolysis.1 Primary PCI has been considered in the American College of Cardiology/American Heart Association (ACC/AHA) guidelines in 1999 to be an alternative to thrombolysis.2 Since then, the number of trials and number of patients randomized has more than doubled to 21 trials and 6800 patients, all of which show clear benefit of PCI over thrombolysis. A meta-analysis of the randomized trials carried out through 1997 showed a clear reduction in mortality, recurrent MI, stroke, and intracranial hemorrhage. Mortality was reduced a relative 34% (6.5% for thrombolysis vs 4.4% for primary PCI), suggesting that 20 patients' lives would be saved for every 1000 patients treated with primary PCI instead of thrombolytic therapy.3 Nonfatal reinfarction was . . . [Full Text of this Article]

Author Affiliation: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.


RELATED LETTER

Thrombolytic Therapy vs Angioplasty in Acute Myocardial Infarction
Christoph Pechlaner, Romuald Bellmann, Aynna Yee, Arash Gabayan, Enrique V. Carbajal, and Thomas Aversano
JAMA. 2002;288(18):2263-2264.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Thrombolytic Therapy vs Primary Percutaneous Coronary Intervention for Myocardial Infarction in Patients Presenting to Hospitals Without On-site Cardiac Surgery: A Randomized Controlled Trial
Thomas Aversano, Lynnet T. Aversano, Eugene Passamani, Genell L. Knatterud, Michael L. Terrin, David O. Williams, Sandra A. Forman, and for the Atlantic Cardiovascular Patient Outcomes Research Team
JAMA. 2002;287(15):1943-1951.
ABSTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Relation Between Hospital Specialization With Primary Percutaneous Coronary Intervention and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction: National Registry of Myocardial Infarction-4 Analysis
Nallamothu et al.
Circulation 2006;113:222-229.
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The Case for Community Hospital Angioplasty
Wharton et al.
Circulation 2005;112:3509-3534.
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Outcomes of Percutaneous Coronary Interventions Performed at Centers Without and With Onsite Coronary Artery Bypass Graft Surgery
Wennberg et al.
JAMA 2004;292:1961-1968.
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Introduction: the origins and implications of a growing shortage of cardiologists
Fye
J Am Coll Cardiol 2004;44:221-232.
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Determinants of treatment strategies and survival in acute myocardial infarction: a population-based study in the Florence district, Italy: Results of the acute myocardial infarction Florence registry (AMI-Florence),
Buiatti et al.
Eur Heart J 2003;24:1195-1203.
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Regionalization and the Underuse of Angiography in the Veterans Affairs Health Care System as Compared with a Fee-for-Service System
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NEJM 2003;348:2209-2217.
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Regionalization of Care for Acute Ischemic Heart Disease: A Call for Specialized Centers
Topol and Kereiakes
Circulation 2003;107:1463-1466.
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Thrombolytic Therapy vs Angioplasty in Acute Myocardial Infarction
Pechlaner et al.
JAMA 2002;288:2263-2264.
FULL TEXT  

Primary PCI vs. Thrombolysis at Hospitals Without On-Site Cardiac Surgery
Journal Watch Cardiology 2002;2002:2-2.
FULL TEXT  





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