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"Crack Kids" Revisited

Barry Zuckerman, MD; Deborah A. Frank, MD; Linda Mayes, MD

JAMA. 2002;287:1990-1991.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of THE JOURNAL, Singer and colleagues¹ report the findings from their prospective cohort study assessing the relationship between prenatal cocaine exposure and cognitive and developmental outcomes in 218 cocaine-exposed infants and 197 unexposed infants. After controlling for prenatal exposure to other drugs, gestational age and size at birth, and a number of caregiver characteristics, the authors found that infants who had in utero cocaine exposure scored on average 6 points lower than the comparison group on the Mental Scale of the Bayley Scales of Infant Development² at 24 months of age. Rates of clinically important developmental delay on the scale were doubled in the cocaine-exposed group compared with the unexposed group (13.7% vs 7.1%, respectively).

The study by Singer et al is the only 1 of 10 peer-reviewed,³ adequately controlled, large-scale, prospective longitudinal studies to show an . . . [Full Text of this Article]

Author Affiliations: Department of Pediatrics, Boston University School of Medicine, Boston, Mass (Drs Zuckerman and Frank); and Department of Child Psychiatry, Yale University School of Medicine, New Haven, Conn (Dr Mayes).

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