ARCHIVES OF OPHTHALMOLOGY
A Randomized Trial of Atropine vs Patching for Treatment of Moderate Amblyopia in Children
The Pediatric Eye Disease Investigator Group
Objective To compare patching and atropine as treatments for moderate amblyopia in children younger than 7 years.
Methods In a randomized clinical trial, 419 children younger than 7 years with amblyopia and visual acuity in the range of 20/40 to 20/100 were assigned to receive either patching or atropine at 47 clinical sites.
Main Outcome Measure Visual acuity in the amblyopic eye and sound eye after 6 months.
Results Visual acuity in the amblyopic eye improved in both groups (improvement from baseline to 6 months was 3.16 lines in the patching group and 2.84 lines in the atropine group). Improvement was initially faster in thepatching group, but after 6 months, the difference in visual acuity between treatment groups was small and . . . [Full Text of this Article]