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Progress and Promise of Diabetes Research
Christopher D. Saudek, MD
JAMA. 2002;287:2582-2584.
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The epidemic of diabetes has taken hold and is extending to new populations. The prevalence of type 2 diabetes in children1 and in developing nations2 has increased dramatically, and adult-onset type 1 diabetes is now well recognized.3 Diabetic cardiovascular disease has become a worldwide burden.4 While new cases of heart disease and cancer are stable or decreasing, the incidence of diabetes has increased 6% annually in the United States5 and more than that in developing countries.6 The human and economic toll of diabetes increases correspondingly, and this requires an integrated, global response. However, policy makers, insurance companies, and the general public are just beginning to recognize the seriousness of diabetes.
Opportunities for progress are virtually limitless, with some of the most fundamental questions raised by diabetes remaining unanswered: What underlies the metabolic syndrome?7-8 What exactly mediates the link between obesity and insulin resistance? Can this resistance . . . [Full Text of this Article]
Author Affiliations: Johns Hopkins University School of Medicine, Baltimore, Md, and American Diabetes Association, Alexandria, Va.
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