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Kristine Y. Lain, MD; James M. Roberts, MD

JAMA. 2002;287:3183-3186.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Preeclampsia is a pregnancy-specific form of hypertension that presents a major health problem worldwide. Preeclampsia complicates 5% to 8% of all pregnancies and increases both maternal and neonatal morbidity and mortality.^1-2 The mainstay of therapy for preeclampsia remains clinical recognition through prenatal care and termination of the disease process with delivery. Maternal mortality has been reduced in the United States, but in countries where prenatal care is not adequate, preeclampsia/eclampsia accounts for 40% to 80% of maternal deaths, an estimated 50 000 per year. Many of these deaths may be preventable with prenatal care and evidence-based prophylactic seizure therapy.

Infants of women with preeclampsia have a 5-fold increase in mortality compared with infants of mothers without the disorder. Much of the neonatal mortality is attributable to iatrogenic prematurity. Approximately 10% of preeclampsia occurs before 34 weeks' gestational age, and indicated delivery for preeclampsia . . . [Full Text of this Article]

Definitions of Hypertensive Disorders in Pregnancy

Pathogenesis of Preeclampsia

Current Management Strategies

Antepartum Assessment

Intrapartum Management

Postpartum Care

Conclusion

Author Affiliations: Magee-Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pa.

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