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Donald C. Goff, MD, Discussant

JAMA. 2002;287:3249-3257.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

DR REYNOLDS: Mr X is a 23-year-old man with a 5-year history of schizophrenia. He lives near Boston and has state health insurance.

Mr X began to have social withdrawal and isolation around age 16, when he dropped out of school sports, went from being an excellent student to barely passing, and began spending much of his free time alone watching videos. He was using alcohol, cannabis, and LSD (lysergic acid diethylamide). He had progressively paranoid delusions: he believed that the Mafia was going to make him a movie star, that bystanders stared at him because they knew he was famous, and that the Mafia was broadcasting to him and controlling his mind. He also believed that his family members were out to get him, that he might not be related to them, and that others questioned his sexual orientation. When one day, . . . [Full Text of this Article]

MR X: HIS VIEW

AT THE CROSSROADS: QUESTIONS FOR DR GOFF

What Is Schizophrenia?

Epidemiology, Risk Factors, and Genetics

Course and Prognosis

Neurobiology

Treatment

Recommendations

QUESTIONS AND DISCUSSION

Author Affiliation: Dr Goff is Associate Professor of Psychiatry, Harvard Medical School; Director, Schizophrenia Program of the Massachusetts General Hospital; and Medical Director, Freedom Trail Clinic, Erich Lindemann Mental Health Center, Boston, Mass.

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