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Food for Thought

Daniel J. Foley, MS; Lon R. White, MD

JAMA. 2002;287:3261-3263.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The risk of acquiring Alzheimer disease (AD) is considerable in countries with long life expectancies. Projected national burdens related to AD are daunting as unprecedented numbers of people are expected to survive their eighth and ninth decades of life.¹ In the United States, the current estimate of 360 000 new cases of AD each year is expected to triple in the next 40 years.² Even modestly effective interventions that delay the onset of AD by 1 to 3 years will substantially alleviate the growing economic and societal burden associated with this disease.³

The role of oxidative stress in the etiology of AD has been hypothesized, described, and supported by a variety of experimental and clinical studies.^4-5 This research has promoted interest in assessing antioxidants for their possible benefits in modifying the course, reducing the risk, or delaying the onset of AD.^6-7 In this . . . [Full Text of this Article]

Author Affiliations: National Institute on Aging, Bethesda, Md (Mr Foley); Pacific Health Research Institute, Honolulu, Hawaii (Dr White).

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