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edited by Irwin M. Arias, James L. Boyer, Nelson Fausto, Francis V. Chisari, David Schachter, and David A. Shafritz, 4th ed, 1088 pp, with illus, $210, ISBN 0-7817-2390-6, Philadelphia, Pa, Lippincott Williams & Wilkins, 2001.

JAMA. 2002;287:524-525.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

This edition appearing after 7 years "strives to bridge the ever-increasing gap between the amazing advances in basic biology and their application to liver structure, function and disease."

All chapters in this volume are completely rewritten, often by new authors, and there are 28 new chapters. Seven broad sections make up the book, starting with an introduction discussing liver organization and embryology. Cells, the subject of the second section, comprise a third of the book. Sections follow on interrelated cell functions, the liver as organ, and relationship to other organs. The last two sections are on pathobiologic analysis, covering such subjects as portal hypertension, liver fibrosis, and interactions of virus with the liver, and "Horizons," 12 chapters on totally new and often poorly understood areas.

Each chapter is a free-standing monograph with appropriate references to other chapters and to chapters from the previous edition available on the Web site (an . . . [Full Text of this Article]

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