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A History of Blood Coagulation
by Charles A. Owen, Jr, edited by William L. Nichols and E. J. Walter Bowie, 355 pp, with illus, soft cover, $49.95, ISBN 1-893005-90-9, Rochester, Minn, Mayo Foundation for Medical Education and Research, 2001.
JAMA. 2002;287:1051-1052.
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The rapidly developing science of hemostasis has often left the average physician somewhat confused, if not mystified, by the coagulation cascade, clotting proteins designated by Roman numerals, and the complexities of the plasminogen-plasmin system. Thus, to convey developments from the days of Hippocrates and Galen to the present, one would need more than a litany of historical names. In A History of Blood Coagulation, the late Charles A. Owen, Jr, MD, PhD, has provided a concise description of the hemostatic mechanism to accompany the historical anecdotes. Thus, the reader who is not a "clotter" will have a greater appreciation of the evolution of our understanding of hemostasis.
In addition to blood coagulation, Owen describes the other essential components of the hemostatic mechanism, namely, platelets and fibrinolysis, and the principles of thrombosis and embolism. The book is richly adorned with illustrations, including some 150 photographs of past and present scientists . . . [Full Text of this Article]
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