MMWR. 2002;51:127
The U.S. Department of Defense (DoD), Center for Deployment Health Research at Naval Health Research Center, San Diego, used computerized medical records to conduct a preliminary evaluation of the potential association between the use of anthrax vaccine in the first trimester of pregnancy and the diagnosis of congenital anomalies in children. Review of preliminary data indicated important limitations in computerized medical records that preclude drawing conclusions from this preliminary study. Investigators are conducting a systematic evaluation of original medical records, including vaccination and infant health records. This evaluation will require several months.
Although the Food and Drug Administration-licensed vaccine has not been suspected to be a hazard to reproductive health, no studies of animals or pregnant women have been conducted, and the vaccine is neither recommended nor licensed for use in pregnancy. DoD continues to maintain a policy of avoiding anthrax vaccination of pregnant women. Because of the . . . [Full Text of this Article]