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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: Dr Aversano and colleagues¹ found that primary percutaneous coronary intervention (PCI) resulted in better outcomes than thrombolytic therapy in patients with acute myocardial infarction (MI). We are concerned that the results may be confounded by medications likely to modify the outcome. In particular, it would be helpful to know the proportions of patients who actually received glycoprotein IIb/IIIa inhibitors, other platelet function inhibitors, low-molecular-weight heparin, -blockers, angiotensin-converting enzyme inhibitors, and cholesterol-lowering drugs.

Christoph Pechlaner, MD; Romuald Bellmann, MD
Innsbruck University Hospital
Innsbruck, Austria

1. Aversano T, Aversano LT, Passamani E, et al for the Atlantic Cardiovascular Patient Outcomes Research Team (C-PORT). Thrombolytic therapy vs primary percutaneous coronary intervention for myocardial infarction in patients presenting to hospitals without on-site cardiac surgery: a randomized controlled trial. JAMA. 2002;287:1943-1951. FREE FULL TEXT

To the Editor: We have several concerns about the study by Dr Aversano and colleagues.¹ First, the study was only single-blind. Because of the nature of the randomized groups, follow-up and management of patients with primary PCI could lead to unrecognized bias introduced into the study in the form of preferential management of PCI patients. This potential bias could have been minimized if enrolled . . . [Full Text of this Article]

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