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  Vol. 288 No. 23, December 18, 2002 TABLE OF CONTENTS
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Banking (on) Genes

DNA Sought as Key to Disease Causes and Cures

Mike Mitka

JAMA. 2002;288:2951-2952.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Geneticists believe they will need DNA samples from hundreds of thousands of people before they have amassed enough data to make possible the identification and treatment of certain diseases resulting from interactions between genes and the environment.

To collect, analyze, and store such vast quantities of DNA, gene banks are being created around the world. Two such ventures were initiated this fall at Northwestern University in Chicago and the Marshfield Clinic in Marshfield, Wis. Investigators at each center want to enroll at least 100 000 people within a decade, study and store their DNA, and make data available to other researchers.

Smaller genetic studies have been successful in the isolation of single genes that, when mutated, cause disorders with lower prevalence, such as Huntington's disease. But researchers believe more common disorders such as cancer, heart disease, and Alzheimer disease involve multiple genes and their interactions with the environment, meaning . . . [Full Text of this Article]



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

US and Scottish Health Professionals' Attitudes toward DNA Biobanking
Leiman et al.
J. Am. Med. Inform. Assoc. 2008;15:357-362.
ABSTRACT | FULL TEXT  





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