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Vaccine Safety

Yvonne A. Maldonado, MD

JAMA. 2002;288:3155-3158.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Vaccination is ranked as one of the 10 greatest public health achievements of the last century and is the number one contribution to decreased global morbidity and mortality.^1-3 Pediatric vaccinations have had the most profound impact of any intervention on increasing global child survival, accounting for 3 million pediatric lives saved annually.³ However, even in the 21st century, vaccine-preventable infectious diseases remain important causes of morbidity and mortality in many areas of the world. Globally, tetanus, measles, and pertussis are the main vaccine-preventable causes of death in children; septicemia and influenza-related pneumonia are among the top 10 causes of death in adults and children worldwide, including the United States.^4-5

Although US pediatric vaccination rates remain high, there is a small but vocal antivaccine movement concerned about vaccine safety that may affect vaccination efforts in the United States and elsewhere.⁶ In adults, vaccine-preventable diseases result . . . [Full Text of this Article]

Recommended Pediatric and Adult Vaccination Schedules

Risks and Benefits

Misconceptions

Review of Perceived Vaccine Risks

Tracking Vaccine-Associated Adverse Events

Current Challenges in Development

Sources of Information

Author Affiliations: Department of Pediatrics, Stanford University School of Medicine, Stanford, and Lucile Salter Packard Children's Hospital at Stanford, Palo Alto, Calif.

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