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Annette Flanagin, RN, MA; Phil B. Fontanarosa, MD; Catherine D. DeAngelis, MD, MPH

JAMA. 2002;288:3166-3168.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Major clinical research investigations, especially large multicenter trials, require the involvement, cooperation, and dedication of many individuals. Roles and responsibilities range from conceiving the study and designing the protocol to collecting and analyzing the data, and numerous essential steps in between. Following completion of the study, the most important responsibilities are prompt preparation of a manuscript that reports the study findings, and timely submission of the paper to a journal for peer review, publication, and communication of the study findings to the scientific and clinical communities.

The number of collaborative studies and multicenter clinical trials seems to be growing, with increasing numbers of published articles involving a study group. For instance, 22% of the 185 research articles published in JAMA as Original Contributions in 2001 specifically identified a study group, compared with 6% of 172 Original Contributions . . . [Full Text of this Article]

Author Affiliations: Ms Flanagin is Managing Senior Editor, Dr Fontanarosa is Executive Deputy Editor, and Dr DeAngelis is Editor, JAMA, Chicago, Ill.

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