This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on ISI (1)  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in JAMA

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: In response to Drs Grodstein and Manson, HRT use is associated with higher SES,^1-2 and lower SES is an important risk factor for CHD and overall mortality.^3-4 Because of these relationships, we believe that it is appropriate to consider SES as a potentially important confounder of the relationship between HRT and CHD. When reviewing the relationship of HRT to other outcomes for this review, we also considered the effect of SES, as well as many other potential confounders.¹

We are aware that women in the NHS were matched for level of education. However, there may be sufficient variation in the level of education and SES of the NHS cohort that we excluded it from our calculation of SES-adjusted studies in the meta-analysis. Nonetheless, we recomputed our results after including the NHS in our SES-adjusted meta-analysis. As shown in Table 1, the pooled RR estimates change slightly and . . . [Full Text of this Article]

RELATED ARTICLES

Relationship Between Hormone Replacement Therapy, Socioeconomic Status, and Coronary Heart Disease
Francine Grodstein and JoAnn E. Manson
JAMA. 2003;289(1):44.
EXTRACT | FULL TEXT  

Postmenopausal Hormone Replacement Therapy: Scientific Review
Heidi D. Nelson, Linda L. Humphrey, Peggy Nygren, Steven M. Teutsch, and Janet D. Allan
JAMA. 2002;288(7):872-881.
ABSTRACT | FULL TEXT  

Socioeconomic Factors, Health Behaviors, and Mortality: Results From a Nationally Representative Prospective Study of US Adults
Paula M. Lantz, James S. House, James M. Lepkowski, David R. Williams, Richard P. Mero, and Jieming Chen
JAMA. 1998;279(21):1703-1708.
ABSTRACT | FULL TEXT